Congenital hypothyroidism impairs spine growth of dentate granule cells by downregulation of CaMKIV

Congenital hypothyroidism (CH), a common neonatal endocrine disorder, can result in cognitive deficits if delay in diagnose and treatment. Dentate gyrus (DG) is the severely affected subregion of the hippocampus by the CH, where the dentate granule cells (DGCs) reside in. However, how CH impairs the...

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Detalles Bibliográficos
Autores principales: Tang, Qingying, Chen, Shuxia, Wu, Hui, Song, Honghua, Wang, Yongjun, Shi, Jinlong, Wu, Youjia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203692/
https://www.ncbi.nlm.nih.gov/pubmed/34127648
http://dx.doi.org/10.1038/s41420-021-00530-z

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203692/
https://www.ncbi.nlm.nih.gov/pubmed/34127648
http://dx.doi.org/10.1038/s41420-021-00530-z

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