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Glycan reactive anti-HIV-1 antibodies bind the SARS-CoV-2 spike protein but do not block viral entry

The SARS-CoV-2 spike glycoprotein is a focal point for vaccine immunogen and therapeutic antibody design, and also serves as a critical antigen in the evaluation of immune responses to COVID-19. A common feature amongst enveloped viruses such as SARS-CoV-2 and HIV-1 is the propensity for displaying...

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Detalles Bibliográficos
Autores principales: Mannar, Dhiraj, Leopold, Karoline, Subramaniam, Sriram
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203731/
https://www.ncbi.nlm.nih.gov/pubmed/34127709
http://dx.doi.org/10.1038/s41598-021-91746-7