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Pan-cancer analysis of SETD2 mutation and its association with the efficacy of immunotherapy

Histone methyltransferase SETD2 plays a critical role in maintaining genomic integrity and stability. Here, we investigated the characteristics of SETD2 somatic mutation in the cancer genome atlas pan-cancer cohort. Our data revealed that, compared with SETD2 nonmutant patients, SETD2 mutant patient...

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Detalles Bibliográficos
Autores principales: Lu, Mingdong, Zhao, Bin, Liu, Mengshan, Wu, Le, Li, Yingying, Zhai, Yingna, Shen, Xian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203790/
https://www.ncbi.nlm.nih.gov/pubmed/34127768
http://dx.doi.org/10.1038/s41698-021-00193-0