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The power and promise of genetic mapping from Plasmodium falciparum crosses utilizing human liver-chimeric mice
Genetic crosses are most powerful for linkage analysis when progeny numbers are high, parental alleles segregate evenly and numbers of inbred progeny are minimized. We previously developed a novel genetic crossing platform for the human malaria parasite Plasmodium falciparum, an obligately sexual, h...
Autores principales: | , , , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203791/ https://www.ncbi.nlm.nih.gov/pubmed/34127785 http://dx.doi.org/10.1038/s42003-021-02210-1 |