Synaptopathy Mechanisms in ALS Caused by C9orf72 Repeat Expansion

Amyotrophic Lateral Sclerosis (ALS) is a complex neurodegenerative disease caused by degeneration of motor neurons (MNs). ALS pathogenic features include accumulation of misfolded proteins, glutamate excitotoxicity, mitochondrial dysfunction at distal axon terminals, and neuronal cytoskeleton change...

Descripción completa

Detalles Bibliográficos
Autores principales: Nishimura, Agnes L., Arias, Natalia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Cellular Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203826/
https://www.ncbi.nlm.nih.gov/pubmed/34140881
http://dx.doi.org/10.3389/fncel.2021.660693

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203826/
https://www.ncbi.nlm.nih.gov/pubmed/34140881
http://dx.doi.org/10.3389/fncel.2021.660693

Ejemplares similares