A novel therapeutic HBV vaccine candidate induces strong polyfunctional cytotoxic T cell responses in mice

BACKGROUND & AIMS: Current standard-of-care suppresses HBV replication, but does not lead to a functional cure. Treatment aiming to cure chronic hepatitis B (CHB) is believed to require the induction of strong cellular immune responses, such as by therapeutic vaccination. METHODS: We designed a...

Descripción completa

Detalles Bibliográficos
Autores principales: Boudewijns, Robbert, Ma, Ji, Neyts, Johan, Dallmeier, Kai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203848/
https://www.ncbi.nlm.nih.gov/pubmed/34159304
http://dx.doi.org/10.1016/j.jhepr.2021.100295

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203848/
https://www.ncbi.nlm.nih.gov/pubmed/34159304
http://dx.doi.org/10.1016/j.jhepr.2021.100295

Ejemplares similares