Rap1 Is Essential for B-Cell Locomotion, Germinal Center Formation and Normal B-1a Cell Population

Integrin regulation by Rap1 is indispensable for lymphocyte recirculation. In mice having B-cell-specific Rap1a/b double knockouts (DKO), the number of B cells in lymph nodes decreased to approximately 4% of that of control mice, and B cells were present in the spleen and blood. Upon the immunizatio...

Descripción completa

Detalles Bibliográficos
Autores principales: Ishihara, Sayaka, Sato, Tsuyoshi, Sugioka, Risa, Miwa, Ryota, Saito, Haruka, Sato, Ryota, Fukuyama, Hidehiro, Nakajima, Akihiko, Sawai, Satoshi, Kotani, Ai, Katagiri, Koko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203927/
https://www.ncbi.nlm.nih.gov/pubmed/34140948
http://dx.doi.org/10.3389/fimmu.2021.624419

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8203927/
https://www.ncbi.nlm.nih.gov/pubmed/34140948
http://dx.doi.org/10.3389/fimmu.2021.624419

Ejemplares similares