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Silencing of the Long Non-Coding RNA TTN-AS1 Attenuates the Malignant Progression of Osteosarcoma Cells by Regulating the miR-16-1-3p/TFAP4 Axis

OBJECTIVES: Osteosarcoma (OS) is a type of bone malignancy. This study attempted to explore the effect of long non-coding RNA TTN-AS1 (TTN-AS1) on OS and to determine its molecular mechanisms. METHODS: The expression of TTN-AS1, microRNA-16-1-3p (miR-16-1-3p), and transcription factor activating enh...

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Detalles Bibliográficos
Autores principales: Meng, Xianghai, Zhang, Zhenjun, Chen, Lin, Wang, Xi, Zhang, Qingguo, Liu, Shuheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204018/
https://www.ncbi.nlm.nih.gov/pubmed/34141611
http://dx.doi.org/10.3389/fonc.2021.652835