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Tumor Genotyping and Homologous Recombination Repair Gene Variants in Patients With Epithelial Ovarian Cancer: Is Pathogenic Enough?

Our hypothesis was that the predictive accuracy of pathogenic variants in genes participating in the homologous recombination repair (HRR) system in patients with epithelial ovarian cancer (EOC) could be improved by considering additional next-generation sequencing (NGS) metrics. NGS genotyping was...

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Detalles Bibliográficos
Autores principales: Fountzilas, Elena, Kotoula, Vassiliki, Koliou, Georgia-Angeliki, Liontos, Michalis, Papadopoulou, Kyriaki, Giannoulatou, Eleni, Papanikolaou, Alexios, Tikas, Ioannis, Chrisafi, Sofia, Mauri, Davide, Chatzopoulos, Kyriakos, Fostira, Florentia, Pectasides, Dimitrios, Oikonomopoulos, Georgios, Aivazi, Dimitra, Andrikopoulou, Angeliki, Visvikis, Anastasios, Aravantinos, Gerasimos, Zagouri, Flora, Fountzilas, George
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204021/
https://www.ncbi.nlm.nih.gov/pubmed/34141624
http://dx.doi.org/10.3389/fonc.2021.683057