MEK1/2 Inhibition Synergistically Enhances the Preventive Effects of Normobaric Oxygen on Spinal Cord Injury in Decompression Sickness Rats

A previous study from our team found that hyperbaric oxygen (HBO) pretreatment attenuated decompression sickness (DCS) spinal cord injury by upregulating heat shock protein 32 (HSP32) via the ROS/p38 MAPK pathway. Meanwhile, a MEK1/2-negative regulatory pathway was also activated to inhibit HSP32 ov...

Descripción completa

Detalles Bibliográficos
Autores principales: Zhou, Quan, Meng, Xiangyang, Huang, Guoyang, Yi, Hongjie, Zheng, Juan, Zhang, Kun, Xu, Weigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Physiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204088/
https://www.ncbi.nlm.nih.gov/pubmed/34140895
http://dx.doi.org/10.3389/fphys.2021.674430

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204088/
https://www.ncbi.nlm.nih.gov/pubmed/34140895
http://dx.doi.org/10.3389/fphys.2021.674430

Ejemplares similares