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On-chip perivascular niche supporting stemness of patient-derived glioma cells in a serum-free, flowable culture

Glioblastoma multiforme (GBM) is the most common and the most aggressive type of primary brain malignancy. Glioblastoma stem-like cells (GSCs) can migrate in vascular niches within or away from the tumour mass, increasing tumour resistance to treatments and contributing to relapses. To study individ...

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Detalles Bibliográficos
Autores principales: Gerigk, Magda, Bulstrode, Harry, Shi, HaoTian Harvey, Tönisen, Felix, Cerutti, Camilla, Morrison, Gillian, Rowitch, David, Huang, Yan Yan Shery
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204159/
https://www.ncbi.nlm.nih.gov/pubmed/33969368
http://dx.doi.org/10.1039/d1lc00271f