IGF1 receptor inhibition amplifies the effects of cancer drugs by autophagy and immune-dependent mechanisms

BACKGROUND: Pharmacological autophagy enhancement constitutes a preclinically validated strategy for preventing or treating most major age-associated diseases. Driven by this consideration, we performed a high-content/high-throughput screen on 65 000 distinct compounds on a robotized fluorescence mi...

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Detalles Bibliográficos
Autores principales: Wu, Qi, Tian, Ai-Ling, Li, Bei, Leduc, Marion, Forveille, Sabrina, Hamley, Peter, Galloway, Warren, Xie, Wei, Liu, Peng, Zhao, Liwei, Zhang, Shuai, Hui, Pan, Madeo, Frank, Tu, Yi, Kepp, Oliver, Kroemer, Guido
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BMJ Publishing Group 2021
Materias:
Basic Tumor Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204183/
https://www.ncbi.nlm.nih.gov/pubmed/34127545
http://dx.doi.org/10.1136/jitc-2021-002722

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204183/
https://www.ncbi.nlm.nih.gov/pubmed/34127545
http://dx.doi.org/10.1136/jitc-2021-002722

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