Dual arginine recognition of LRRK2 phosphorylated Rab GTPases

Parkinson’s-disease-associated LRRK2 is a multidomain Ser/Thr kinase that phosphorylates a subset of Rab GTPases to control their effector functions. Rab GTPases are the prime regulators of membrane trafficking in eukaryotic cells. Rabs exert their biological effects by recruitment of effector prote...

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Detalles Bibliográficos
Autores principales: Waschbüsch, Dieter, Purlyte, Elena, Khan, Amir R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204342/
https://www.ncbi.nlm.nih.gov/pubmed/33887226
http://dx.doi.org/10.1016/j.bpj.2021.03.030

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204342/
https://www.ncbi.nlm.nih.gov/pubmed/33887226
http://dx.doi.org/10.1016/j.bpj.2021.03.030

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