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Energy landscape remodeling mechanism of Hsp70-chaperone-accelerated protein folding

Hsp70 chaperone is one of the key protein machines responsible for the quality control of protein production in cells. Facilitating in vivo protein folding by counteracting misfolding and aggregation is the essence of its biological function. Although the allosteric cycle during its functional actio...

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Detalles Bibliográficos
Autores principales: Lu, Jiajun, Zhang, Xiaoyi, Wu, Yichao, Sheng, Yuebiao, Li, Wenfei, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Biophysical Society 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204389/
https://www.ncbi.nlm.nih.gov/pubmed/33745889
http://dx.doi.org/10.1016/j.bpj.2021.03.013