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Energy landscape remodeling mechanism of Hsp70-chaperone-accelerated protein folding
Hsp70 chaperone is one of the key protein machines responsible for the quality control of protein production in cells. Facilitating in vivo protein folding by counteracting misfolding and aggregation is the essence of its biological function. Although the allosteric cycle during its functional actio...
Autores principales: | Lu, Jiajun, Zhang, Xiaoyi, Wu, Yichao, Sheng, Yuebiao, Li, Wenfei, Wang, Wei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Biophysical Society
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204389/ https://www.ncbi.nlm.nih.gov/pubmed/33745889 http://dx.doi.org/10.1016/j.bpj.2021.03.013 |
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