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MiR-194-5p enhances the sensitivity of nonsmall-cell lung cancer to doxorubicin through targeted inhibition of hypoxia-inducible factor-1

BACKGROUND: Despite chemotherapy being a common treatment, an increase in chemoresistance over time is unavoidable. We therefore investigated the role of miR-194-5p in regulating chordoma cell behavior and examined the downstream effectors of miR-194-5p. METHODS: In this study, NSCLC cell lines A549...

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Detalles Bibliográficos
Autores principales: Xia, Mengning, Sheng, Lili, Qu, Wei, Xue, Xue, Chen, Hucheng, Zheng, Guoyan, Chen, Weigang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204537/
https://www.ncbi.nlm.nih.gov/pubmed/34127010
http://dx.doi.org/10.1186/s12957-021-02278-3