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The engineered expression of secreted HSPB5-Fc in CHO cells exhibits cytoprotection in vitro
BACKGROUND: HSPB5 is an ATP-independent molecular chaperone that is induced by heat shock or other proteotoxic stresses. HSPB5 is cytoprotective against stress both intracellularly and extracellularly. It acts as a potential therapeutic candidate in ischemia-reperfusion and neurodegenerative disease...
Autores principales: | , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204567/ https://www.ncbi.nlm.nih.gov/pubmed/34126963 http://dx.doi.org/10.1186/s12896-021-00700-y |