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Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene

We found evidence of late-onset Alzheimer disease (LOAD)-associated genetic polymorphism within an exon of Mucin 6 (MUC6) and immediately downstream from another gene: Adaptor Related Protein Complex 2 Subunit Alpha 2 (AP2A2). PCR analyses on genomic DNA samples confirmed that the size of the MUC6 v...

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Detalles Bibliográficos
Autores principales: Katsumata, Yuriko, Fardo, David W, Bachstetter, Adam D, Artiushin, Sergey C, Wang, Wang-Xia, Wei, Angela, Brzezinski, Lena J, Nelson, Bela G, Huang, Qingwei, Abner, Erin L, Anderson, Sonya, Patel, Indumati, Shaw, Benjamin C, Price, Douglas A, Niedowicz, Dana M, Wilcock, Donna W, Jicha, Gregory A, Neltner, Janna H, Van Eldik, Linda J, Estus, Steven, Nelson, Peter T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204704/
https://www.ncbi.nlm.nih.gov/pubmed/31748784
http://dx.doi.org/10.1093/jnen/nlz116