Cargando…
Alzheimer Disease Pathology-Associated Polymorphism in a Complex Variable Number of Tandem Repeat Region Within the MUC6 Gene, Near the AP2A2 Gene
We found evidence of late-onset Alzheimer disease (LOAD)-associated genetic polymorphism within an exon of Mucin 6 (MUC6) and immediately downstream from another gene: Adaptor Related Protein Complex 2 Subunit Alpha 2 (AP2A2). PCR analyses on genomic DNA samples confirmed that the size of the MUC6 v...
Autores principales: | Katsumata, Yuriko, Fardo, David W, Bachstetter, Adam D, Artiushin, Sergey C, Wang, Wang-Xia, Wei, Angela, Brzezinski, Lena J, Nelson, Bela G, Huang, Qingwei, Abner, Erin L, Anderson, Sonya, Patel, Indumati, Shaw, Benjamin C, Price, Douglas A, Niedowicz, Dana M, Wilcock, Donna W, Jicha, Gregory A, Neltner, Janna H, Van Eldik, Linda J, Estus, Steven, Nelson, Peter T |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2019
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204704/ https://www.ncbi.nlm.nih.gov/pubmed/31748784 http://dx.doi.org/10.1093/jnen/nlz116 |
Ejemplares similares
-
The MUC6/AP2A2 Locus and Its Relevance to Alzheimer’s Disease: A Review
por: Nelson, Peter T, et al.
Publicado: (2020) -
A neuropathologic feature of brain aging: multi-lumen vascular profiles
por: Ighodaro, Eseosa T., et al.
Publicado: (2023) -
Neurodegenerative pathologies associated with behavioral and psychological symptoms of dementia in a community-based autopsy cohort
por: Nelson, Ruth S., et al.
Publicado: (2023) -
In severe ADNC, hippocampi with comorbid LATE-NC and hippocampal sclerosis have substantially more astrocytosis than those with LATE-NC or hippocampal sclerosis alone
por: Niedowicz, Dana M, et al.
Publicado: (2023) -
Longitudinal Trajectories of Cholesterol from Midlife through Late Life according to Apolipoprotein E Allele Status
por: Downer, Brian, et al.
Publicado: (2014)