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Premature Senescence and Increased Oxidative Stress in the Thymus of Down Syndrome Patients

Down syndrome (DS) patients prematurely show clinical manifestations usually associated with aging. Their immune system declines earlier than healthy individuals, leading to increased susceptibility to infections and higher incidence of autoimmune phenomena. Clinical features of accelerated aging in...

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Detalles Bibliográficos
Autores principales: Marcovecchio, Genni Enza, Ferrua, Francesca, Fontana, Elena, Beretta, Stefano, Genua, Marco, Bortolomai, Ileana, Conti, Anastasia, Montin, Davide, Cascarano, Maria Teresa, Bergante, Sonia, D’Oria, Veronica, Giamberti, Alessandro, Amodio, Donato, Cancrini, Caterina, Carotti, Adriano, Di Micco, Raffaella, Merelli, Ivan, Bosticardo, Marita, Villa, Anna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204718/
https://www.ncbi.nlm.nih.gov/pubmed/34140950
http://dx.doi.org/10.3389/fimmu.2021.669893