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Regulation of mTORC1 activity by the Golgi apparatus

Mechanistic (or mammalian) target of rapamycin complex 1 (mTORC1) is a major signalling kinase in cells that regulates proliferation and metabolism and is controlled by extrinsic and intrinsic signals. The lysosome has received considerable attention as a major hub of mTORC1 activation. However, mTO...

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Detalles Bibliográficos
Autores principales: Makhoul, Christian, Gleeson, Paul A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Faculty Opinions Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204759/
https://www.ncbi.nlm.nih.gov/pubmed/34195689
http://dx.doi.org/10.12703/r/10-50