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Cancer Risk Stratification of Anal Intraepithelial Neoplasia in Human Immunodeficiency Virus–Positive Men by Validated Methylation Markers Associated With Progression to Cancer

BACKGROUND: High-grade anal intraepithelial neoplasia (HGAIN; AIN2–3) is highly prevalent in HIV+ men, but only a minority of these lesions progress towards cancer. Currently, cancer progression risk cannot be established; therefore, no consensus exists on whether HGAIN should be treated. This study...

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Detalles Bibliográficos
Autores principales: van der Zee, Ramon P, Richel, Olivier, van Noesel, Carel J M, Ciocănea-Teodorescu, Iuliana, van Splunter, Annina P, ter Braak, Timo J, Nathan, Mayura, Cuming, Tamzin, Sheaff, Michael, Kreuter, Alexander, Meijer, Chris J L M, Quint, Wim G V, de Vries, Henry J C, Prins, Jan M, Steenbergen, Renske D M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204787/
https://www.ncbi.nlm.nih.gov/pubmed/32266940
http://dx.doi.org/10.1093/cid/ciaa397