Structural basis of TRAPPIII‐mediated Rab1 activation

The GTPase Rab1 is a master regulator of the early secretory pathway and is critical for autophagy. Rab1 activation is controlled by its guanine nucleotide exchange factor, the multisubunit TRAPPIII complex. Here, we report the 3.7 Å cryo‐EM structure of the Saccharomyces cerevisiae TRAPPIII complex...

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Detalles Bibliográficos
Autores principales: Joiner, Aaron MN, Phillips, Ben P, Yugandhar, Kumar, Sanford, Ethan J, Smolka, Marcus B, Yu, Haiyuan, Miller, Elizabeth A, Fromme, J Christopher
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204860/
https://www.ncbi.nlm.nih.gov/pubmed/34018207
http://dx.doi.org/10.15252/embj.2020107607

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204860/
https://www.ncbi.nlm.nih.gov/pubmed/34018207
http://dx.doi.org/10.15252/embj.2020107607

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