Cancer‐associated POT1 mutations lead to telomere elongation without induction of a DNA damage response

Mutations in the shelterin protein POT1 are associated with chronic lymphocytic leukemia (CLL), Hodgkin lymphoma, angiosarcoma, melanoma, and other cancers. These cancer‐associated POT1 (caPOT1) mutations are generally heterozygous, missense, or nonsense mutations occurring throughout the POT1 readi...

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Detalles Bibliográficos
Autores principales: Kim, Won‐Tae, Hennick, Kelsey, Johnson, Joshua, Finnerty, Brendan, Choo, Seunga, Short, Sarah B, Drubin, Casey, Forster, Ryan, McMaster, Mary L, Hockemeyer, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204863/
https://www.ncbi.nlm.nih.gov/pubmed/33934394
http://dx.doi.org/10.15252/embj.2020107346

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204863/
https://www.ncbi.nlm.nih.gov/pubmed/33934394
http://dx.doi.org/10.15252/embj.2020107346

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