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Overall survival in metastatic melanoma correlates with pembrolizumab exposure and T cell exhaustion markers

Trial data support an absence of an exposure–survival relationship for pembrolizumab. As these relationships remain unexamined in a real‐world setting, we determined them in metastatic melanoma prospectively in an observational study. Translational objectives included identifying biomarkers of progr...

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Detalles Bibliográficos
Autores principales: Navani, Vishal, Graves, Moira C., Marchett, Giovana Celli, Mandaliya, Hiren, Bowden, Nikola A., van der Westhuizen, Andre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8204864/
https://www.ncbi.nlm.nih.gov/pubmed/34129290
http://dx.doi.org/10.1002/prp2.808