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Novel CD123 polyaptamer hydrogel edited by Cas9/sgRNA for AML-targeted therapy
CD123 targeting molecules have been widely applied in acute myelocytic leukemia (AML) therapeutics. Although antibodies have been more widely used as targeting molecules, aptamer have unique advantages for CD123 targeting therapy. In this study, we constructed an aptamer hydrogel termed as SSFH whic...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Taylor & Francis
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205012/ https://www.ncbi.nlm.nih.gov/pubmed/34121564 http://dx.doi.org/10.1080/10717544.2021.1934191 |