Novel CD123 polyaptamer hydrogel edited by Cas9/sgRNA for AML-targeted therapy

CD123 targeting molecules have been widely applied in acute myelocytic leukemia (AML) therapeutics. Although antibodies have been more widely used as targeting molecules, aptamer have unique advantages for CD123 targeting therapy. In this study, we constructed an aptamer hydrogel termed as SSFH whic...

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Detalles Bibliográficos
Autores principales: Wu, Haibin, Zhang, Liyu, Zhu, Zeen, Ding, Chenxi, Chen, Shengquan, Liu, Ruiping, Fan, Huafeng, Chen, Yang, Li, Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205012/
https://www.ncbi.nlm.nih.gov/pubmed/34121564
http://dx.doi.org/10.1080/10717544.2021.1934191

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