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Ischemia-induced upregulation of autophagy preludes dysfunctional lysosomal storage and associated synaptic impairments in neurons

Macroautophagy/autophagy is vital for neuronal homeostasis and functions. Accumulating evidence suggest that autophagy is impaired during cerebral ischemia, contributing to neuronal dysfunction and neurodegeneration. However, the outcomes after transient modification in autophagy machinery are not f...

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Detalles Bibliográficos
Autores principales: Zhang, Xia, Wei, Mengping, Fan, Jiahui, Yan, Weijie, Zha, Xu, Song, Huimeng, Wan, Rongqi, Yin, Yanling, Wang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205014/
https://www.ncbi.nlm.nih.gov/pubmed/33111641
http://dx.doi.org/10.1080/15548627.2020.1840796