Methoxy and bromo scans on N-(5-methoxyphenyl) methoxybenzenesulphonamides reveal potent cytotoxic compounds, especially against the human breast adenocarcinoma MCF7 cell line

Thirty seven N-(5-methoxyphenyl)-4-methoxybenzenesulphonamide with methoxy or/and bromo substitutions (series 1-4) and with different substituents on the sulphonamide nitrogen have been synthesised. 21 showed sub-micromolar cytotoxicity against HeLa and HT-29 human tumour cell lines, and were partic...

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Detalles Bibliográficos
Autores principales: González, Myriam, Ovejero-Sánchez, María, Vicente-Blázquez, Alba, Medarde, Manuel, González-Sarmiento, Rogelio, Peláez, Rafael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Taylor & Francis 2021
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205030/
https://www.ncbi.nlm.nih.gov/pubmed/34107837
http://dx.doi.org/10.1080/14756366.2021.1925265

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205030/
https://www.ncbi.nlm.nih.gov/pubmed/34107837
http://dx.doi.org/10.1080/14756366.2021.1925265

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