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Activity-mediated accumulation of potassium induces a switch in firing pattern and neuronal excitability type
During normal neuronal activity, ionic concentration gradients across a neuron’s membrane are often assumed to be stable. Prolonged spiking activity, however, can reduce transmembrane gradients and affect voltage dynamics. Based on mathematical modeling, we investigated the impact of neuronal activi...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Public Library of Science
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205125/ https://www.ncbi.nlm.nih.gov/pubmed/34043638 http://dx.doi.org/10.1371/journal.pcbi.1008510 |