Quantitative Profiling of WNT-3A Binding to All Human Frizzled Paralogues in HEK293 Cells by NanoBiT/BRET Assessments

[Image: see text] The WNT signaling system governs critical processes during embryonic development and tissue homeostasis, and its dysfunction can lead to cancer. Details concerning selectivity and differences in relative binding affinities of 19 mammalian WNTs to the cysteine-rich domain (CRD) of t...

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Detalles Bibliográficos
Autores principales: Kozielewicz, Paweł, Shekhani, Rawan, Moser, Stefanie, Bowin, Carl-Fredrik, Wesslowski, Janine, Davidson, Gary, Schulte, Gunnar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2021
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205236/
https://www.ncbi.nlm.nih.gov/pubmed/34151213
http://dx.doi.org/10.1021/acsptsci.1c00084

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205236/
https://www.ncbi.nlm.nih.gov/pubmed/34151213
http://dx.doi.org/10.1021/acsptsci.1c00084

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