[(11)C]PK11195-PET Brain Imaging of the Mitochondrial Translocator Protein in Mitochondrial Disease

OBJECTIVE: To explore the possibilities of radioligands against the mitochondrial outer membrane translocator protein (TSPO) as biomarkers for mitochondrial disease, we performed brain PET-MRI with [(11)C]PK11195 in 14 patients with genetically confirmed mitochondrial disease and 33 matched controls...

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Detalles Bibliográficos
Autores principales: van den Ameele, Jelle, Hong, Young T., Manavaki, Roido, Kouli, Antonina, Biggs, Heather, MacIntyre, Zoe, Horvath, Rita, Yu-Wai-Man, Patrick, Reid, Evan, Williams-Gray, Caroline H., Bullmore, Ed T., Aigbirhio, Franklin I., Fryer, Tim D., Chinnery, Patrick F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205464/
https://www.ncbi.nlm.nih.gov/pubmed/33883237
http://dx.doi.org/10.1212/WNL.0000000000012033

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205464/
https://www.ncbi.nlm.nih.gov/pubmed/33883237
http://dx.doi.org/10.1212/WNL.0000000000012033

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