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Value-Generating Exploratory Trials in Neurodegenerative Dementias

Drug development for Alzheimer disease and other neurodegenerative dementias, including frontotemporal dementia, has experienced a long history of phase 2 and phase 3 clinical trials that failed to show efficacy of investigational drugs. Despite differences in clinical and behavioral characteristics...

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Detalles Bibliográficos
Autores principales: Friedman, Lauren G., McKeehan, Nicholas, Hara, Yuko, Cummings, Jeffrey L., Matthews, Dawn C., Zhu, Jian, Mohs, Richard C., Wang, Deli, Hendrix, Suzanne B., Quintana, Melanie, Schneider, Lon S., Grundman, Michael, Dickson, Samuel P., Feldman, Howard H., Jaeger, Judith, Finger, Elizabeth C., Ryan, J. Michael, Niehoff, Debra, Dickinson, Susan L-J., Markowitz, Jessica T., Owen, Meriel, Travaglia, Alessio, Fillit, Howard M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205472/
https://www.ncbi.nlm.nih.gov/pubmed/33674360
http://dx.doi.org/10.1212/WNL.0000000000011774