In Vivo Diagnosis of Synucleinopathies: A Comparative Study of Skin Biopsy and RT-QuIC

OBJECTIVE: To determine whether (1) immunofluorescence is a reproducible technique in detecting misfolded α-synuclein in skin nerves and subsequently whether (2) immunofluorescence and real-time quaking-induced conversion (RT-QuIC) (both in skin and CSF) show a comparable in vivo diagnostic accuracy...

Descripción completa

Detalles Bibliográficos
Autores principales: Donadio, Vincenzo, Wang, Zerui, Incensi, Alex, Rizzo, Giovanni, Fileccia, Enrico, Vacchiano, Veria, Capellari, Sabina, Magnani, Martina, Scaglione, Cesa, Stanzani Maserati, Michelangelo, Avoni, Patrizia, Liguori, Rocco, Zou, Wenquan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205473/
https://www.ncbi.nlm.nih.gov/pubmed/33837116
http://dx.doi.org/10.1212/WNL.0000000000011935

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205473/
https://www.ncbi.nlm.nih.gov/pubmed/33837116
http://dx.doi.org/10.1212/WNL.0000000000011935

Ejemplares similares