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The hepcidin regulator erythroferrone is a new member of the erythropoiesis-iron-bone circuitry

BACKGROUND: Erythroblast erythroferrone (ERFE) secretion inhibits hepcidin expression by sequestering several bone morphogenetic protein (BMP) family members to increase iron availability for erythropoiesis. METHODS: To address whether ERFE functions also in bone and whether the mechanism of ERFE ac...

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Detalles Bibliográficos
Autores principales: Castro-Mollo, Melanie, Gera, Sakshi, Ruiz-Martinez, Marc, Feola, Maria, Gumerova, Anisa, Planoutene, Marina, Clementelli, Cara, Sangkhae, Veena, Casu, Carla, Kim, Se-Min, Ostland, Vaughn, Han, Huiling, Nemeth, Elizabeta, Fleming, Robert, Rivella, Stefano, Lizneva, Daria, Yuen, Tony, Zaidi, Mone, Ginzburg, Yelena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205482/
https://www.ncbi.nlm.nih.gov/pubmed/34002695
http://dx.doi.org/10.7554/eLife.68217