Polymerization of misfolded Z alpha-1 antitrypsin protein lowers CX3CR1 expression in human PBMCs

Expression levels of CX3CR1 (C-X3-C motif chemokine receptor 1) on immune cells have significant importance in maintaining tissue homeostasis under physiological and pathological conditions. The factors implicated in the regulation of CX3CR1 and its specific ligand CX3CL1 (fractalkine) expression re...

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Detalles Bibliográficos
Autores principales: Tumpara, Srinu, Ballmaier, Matthias, Wrenger, Sabine, König, Mandy, Lehmann, Matthias, Lichtinghagen, Ralf, Martinez-Delgado, Beatriz, Korenbaum, Elena, DeLuca, David, Jedicke, Nils, Welte, Tobias, Fromme, Malin, Strnad, Pavel, Stolk, Jan, Janciauskiene, Sabina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2021
Materias:
Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205483/
https://www.ncbi.nlm.nih.gov/pubmed/34002692
http://dx.doi.org/10.7554/eLife.64881

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205483/
https://www.ncbi.nlm.nih.gov/pubmed/34002692
http://dx.doi.org/10.7554/eLife.64881

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