An IFN-STAT Axis Augments Tissue Damage and Inflammation in a Mouse Model of Crohn's Disease

Blocking interferon-function by therapeutic intervention of the JAK-STAT-axis is a novel promising treatment option for inflammatory bowel disease (IBD). Although JAK inhibitors have proven efficacy in patients with active ulcerative colitis (UC), they failed to induce clinical remission in patients...

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Detalles Bibliográficos
Autores principales: Stolzer, Iris, Dressel, Anja, Chiriac, Mircea T., Neurath, Markus F., Günther, Claudia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Medicine
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205542/
https://www.ncbi.nlm.nih.gov/pubmed/34141714
http://dx.doi.org/10.3389/fmed.2021.644244

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205542/
https://www.ncbi.nlm.nih.gov/pubmed/34141714
http://dx.doi.org/10.3389/fmed.2021.644244

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