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An IFN-STAT Axis Augments Tissue Damage and Inflammation in a Mouse Model of Crohn's Disease
Blocking interferon-function by therapeutic intervention of the JAK-STAT-axis is a novel promising treatment option for inflammatory bowel disease (IBD). Although JAK inhibitors have proven efficacy in patients with active ulcerative colitis (UC), they failed to induce clinical remission in patients...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205542/ https://www.ncbi.nlm.nih.gov/pubmed/34141714 http://dx.doi.org/10.3389/fmed.2021.644244 |