Shikonin Attenuates Chronic Cerebral Hypoperfusion-Induced Cognitive Impairment by Inhibiting Apoptosis via PTEN/Akt/CREB/BDNF Signaling

Shikonin (SK) exerts neuroprotective effects; however, to date, its protective effect against chronic cerebral hypoperfusion- (CCH-) induced vascular dementia (VaD) has not been investigated. Therefore, the current study investigated whether SK could mitigate the cognitive deficits caused by CCH. Th...

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Detalles Bibliográficos
Autores principales: Jia, Yanqiu, Li, Zhe, Wang, Tianjun, Fan, Mingyue, Song, Jiaxi, Lv, Peiyuan, Jin, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205575/
https://www.ncbi.nlm.nih.gov/pubmed/34211568
http://dx.doi.org/10.1155/2021/5564246

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205575/
https://www.ncbi.nlm.nih.gov/pubmed/34211568
http://dx.doi.org/10.1155/2021/5564246

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