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Shikonin Attenuates Chronic Cerebral Hypoperfusion-Induced Cognitive Impairment by Inhibiting Apoptosis via PTEN/Akt/CREB/BDNF Signaling

Shikonin (SK) exerts neuroprotective effects; however, to date, its protective effect against chronic cerebral hypoperfusion- (CCH-) induced vascular dementia (VaD) has not been investigated. Therefore, the current study investigated whether SK could mitigate the cognitive deficits caused by CCH. Th...

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Detalles Bibliográficos
Autores principales:	Jia, Yanqiu, Li, Zhe, Wang, Tianjun, Fan, Mingyue, Song, Jiaxi, Lv, Peiyuan, Jin, Wei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205575/ https://www.ncbi.nlm.nih.gov/pubmed/34211568 http://dx.doi.org/10.1155/2021/5564246

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