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Glanzmann Thrombasthenia: Perspectives from Clinical Practice on Accurate Diagnosis and Optimal Treatment Strategies

Glanzmann thrombasthenia (GT) is a rare autosomal recessive disorder of fibrinogen-mediated platelet aggregation due to a quantitative or qualitative deficit of the α(IIb)β(3) integrin at the platelet surface membrane resulting from mutation(s) in ITGA2B and/or ITGB3. Patients tend to present in ear...

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Detalles Bibliográficos
Autores principales: Mathews, Natalie, Rivard, Georges-Etienne, Bonnefoy, Arnaud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205616/
https://www.ncbi.nlm.nih.gov/pubmed/34149292
http://dx.doi.org/10.2147/JBM.S271744