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A Mathematical Study of the Influence of Hypoxia and Acidity on the Evolutionary Dynamics of Cancer
Hypoxia and acidity act as environmental stressors promoting selection for cancer cells with a more aggressive phenotype. As a result, a deeper theoretical understanding of the spatio-temporal processes that drive the adaptation of tumour cells to hypoxic and acidic microenvironments may open up new...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer US
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8205926/ https://www.ncbi.nlm.nih.gov/pubmed/34129102 http://dx.doi.org/10.1007/s11538-021-00914-3 |