Hypoxic TAM-derived exosomal miR-155-5p promotes RCC progression through HuR-dependent IGF1R/AKT/PI3K pathway

Hypoxic tumor-associated macrophages (TAMs) are related to poor prognosis of patients with clear cell renal cell carcinoma (ccRCC). Exosomes are small lipid-bilayer vesicles that implicated in tumor progression and metastasis. However, whether hypoxic TAM-derived exosomes affect RCC progression with...

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Detalles Bibliográficos
Autores principales: Gu, Wenyu, Gong, Linjing, Wu, Xu, Yao, Xudong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206073/
https://www.ncbi.nlm.nih.gov/pubmed/34131104
http://dx.doi.org/10.1038/s41420-021-00525-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206073/
https://www.ncbi.nlm.nih.gov/pubmed/34131104
http://dx.doi.org/10.1038/s41420-021-00525-w

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