Integrated analysis of Xist upregulation and X-chromosome inactivation with single-cell and single-allele resolution

To ensure dosage compensation between the sexes, one randomly chosen X chromosome is silenced in each female cell in the process of X-chromosome inactivation (XCI). XCI is initiated during early development through upregulation of the long non-coding RNA Xist, which mediates chromosome-wide gene sil...

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Detalles Bibliográficos
Autores principales: Pacini, Guido, Dunkel, Ilona, Mages, Norbert, Mutzel, Verena, Timmermann, Bernd, Marsico, Annalisa, Schulz, Edda G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206119/
https://www.ncbi.nlm.nih.gov/pubmed/34131144
http://dx.doi.org/10.1038/s41467-021-23643-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206119/
https://www.ncbi.nlm.nih.gov/pubmed/34131144
http://dx.doi.org/10.1038/s41467-021-23643-6

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