Structural basis of mechano-chemical coupling by the mitotic kinesin KIF14

KIF14 is a mitotic kinesin whose malfunction is associated with cerebral and renal developmental defects and several cancers. Like other kinesins, KIF14 couples ATP hydrolysis and microtubule binding to the generation of mechanical work, but the coupling mechanism between these processes is still no...

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Detalles Bibliográficos
Autores principales: Benoit, Matthieu P.M.H., Asenjo, Ana B., Paydar, Mohammadjavad, Dhakal, Sabin, Kwok, Benjamin H., Sosa, Hernando
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206134/
https://www.ncbi.nlm.nih.gov/pubmed/34131133
http://dx.doi.org/10.1038/s41467-021-23581-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206134/
https://www.ncbi.nlm.nih.gov/pubmed/34131133
http://dx.doi.org/10.1038/s41467-021-23581-3

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