Susceptibility of cyclin-dependent kinase inhibitor 1-deficient mice to rheumatoid arthritis arising from interleukin-1β-induced inflammation

We recently reported that cyclin-dependent kinase inhibitor 1 (p21) deficiency induces osteoarthritis susceptibility. Here, we determined the mechanism underlying the effect of p21 in synovial and cartilage tissues in RA. The knee joints of p21-knockout (p21(−/−)) (n = 16) and wild type C57BL/6 (p21...

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Detalles Bibliográficos
Autores principales: Takashima, Yoshinori, Hayashi, Shinya, Fukuda, Koji, Maeda, Toshihisa, Tsubosaka, Masanori, Kamenaga, Tomoyuki, Kikuchi, Kenichi, Fujita, Masahiro, Kuroda, Yuichi, Hashimoto, Shingo, Nakano, Naoki, Matsumoto, Tomoyuki, Kuroda, Ryosuke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206139/
https://www.ncbi.nlm.nih.gov/pubmed/34131243
http://dx.doi.org/10.1038/s41598-021-92055-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206139/
https://www.ncbi.nlm.nih.gov/pubmed/34131243
http://dx.doi.org/10.1038/s41598-021-92055-9

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