RTP801/REDD1 contributes to neuroinflammation severity and memory impairments in Alzheimer’s disease

RTP801/REDD1 is a stress-regulated protein whose upregulation is necessary and sufficient to trigger neuronal death. Its downregulation in Parkinson’s and Huntington’s disease models ameliorates the pathological phenotypes. In the context of Alzheimer’s disease (AD), the coding gene for RTP801, DDIT...

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Detalles Bibliográficos
Autores principales: Pérez-Sisqués, Leticia, Sancho-Balsells, Anna, Solana-Balaguer, Júlia, Campoy-Campos, Genís, Vives-Isern, Marcel, Soler-Palazón, Ferran, Anglada-Huguet, Marta, López-Toledano, Miguel-Ángel, Mandelkow, Eva-Maria, Alberch, Jordi, Giralt, Albert, Malagelada, Cristina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206344/
https://www.ncbi.nlm.nih.gov/pubmed/34131105
http://dx.doi.org/10.1038/s41419-021-03899-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206344/
https://www.ncbi.nlm.nih.gov/pubmed/34131105
http://dx.doi.org/10.1038/s41419-021-03899-y

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