Cargando…

MicroRNA-326 attenuates immune escape and prevents metastasis in lung adenocarcinoma by targeting PD-L1 and B7-H3

Tumor-infiltrating T cells are highly expressive of inhibitory receptor/immune checkpoint molecules that bind to ligand expressed by tumor cells and antigen-presenting cells, and eventually lead to T cell dysfunction. It is a hot topic to restore T cell function by targeting immune checkpoint. In re...

Descripción completa

Detalles Bibliográficos
Autores principales: Shao, Lijuan, He, Qian, Wang, Jingbo, He, Fei, Lin, Shengcheng, Wu, Liujing, Gao, Yubiao, Ma, Wei, Dong, Jun, Yang, Xiaofei, Li, Furong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206349/
https://www.ncbi.nlm.nih.gov/pubmed/34131111
http://dx.doi.org/10.1038/s41420-021-00527-8