Genome sequencing unveils a regulatory landscape of platelet reactivity

Platelet aggregation at the site of atherosclerotic vascular injury is the underlying pathophysiology of myocardial infarction and stroke. To build upon prior GWAS, here we report on 16 loci identified through a whole genome sequencing (WGS) approach in 3,855 NHLBI Trans-Omics for Precision Medicine...

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Detalles Bibliográficos
Autores principales: Keramati, Ali R., Chen, Ming-Huei, Rodriguez, Benjamin A. T., Yanek, Lisa R., Bhan, Arunoday, Gaynor, Brady J., Ryan, Kathleen, Brody, Jennifer A., Zhong, Xue, Wei, Qiang, Kammers, Kai, Kanchan, Kanika, Iyer, Kruthika, Kowalski, Madeline H., Pitsillides, Achilleas N., Cupples, L. Adrienne, Li, Bingshan, Schlaeger, Thorsten M., Shuldiner, Alan R., O’Connell, Jeffrey R., Ruczinski, Ingo, Mitchell, Braxton D., Faraday, Nauder, Taub, Margaret A., Becker, Lewis C., Lewis, Joshua P., Mathias, Rasika A., Johnson, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206369/
https://www.ncbi.nlm.nih.gov/pubmed/34131117
http://dx.doi.org/10.1038/s41467-021-23470-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206369/
https://www.ncbi.nlm.nih.gov/pubmed/34131117
http://dx.doi.org/10.1038/s41467-021-23470-9

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