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Progress and Promise of Nur77-based Therapeutics for Central Nervous System Disorders

Nur77 belongs to the NR4A subgroup of the nuclear receptor superfamily. Unlike other nuclear receptors, a natural ligand for Nur77 has not been identified yet. However, a few small molecules can interact with this receptor and induce a conformational change to mediate its activity. The expression an...

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Detalles Bibliográficos
Autores principales: Liu, Lu, Ma, Di, Zhuo, La, Pang, Xinyuan, You, Jiulin, Feng, Jiachun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Bentham Science Publishers 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8206462/
https://www.ncbi.nlm.nih.gov/pubmed/32504502
http://dx.doi.org/10.2174/1570159X18666200606231723